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Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.

Hou, Shuang Zhao, Haichao Zhao, Libo Shen, Qinglin Wei, Kevin S Suh, Daniel Y Nakao, Aiko Garcia, Mitch A Song, Min Lee, Tom ...

Published in Advanced materials (Deerfield Beach, Fla.)

A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells ...

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