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A microfluidic platform for sequential ligand labeling and cell binding analysis

Sui, Guodong Lee, Cheng-Chung Kamei, Ken-Ichiro Li, Hua-Jung Wang, Jin-Yi Wang, Jun Herschman, Harvey R. Tseng, Hsian-Rong

Published in Biomedical Microdevices

Developing biochemical and cell biological assay for screening biomolecules, evaluating their characteristics in biological processes, and determining their pharmacological effects represents a key technology in biomedical research. A PDMS-based integrated microfluidic platform was fabricated and tested for facilitating the labeling of ligand on th...

Integrated microfluidic devices for combinatorial cell-based assays

Yu, Zeta Tak For Kamei, Ken-ichiro Takahashi, Hiroko Shu, Chengyi Jenny Wang, Xiaopu He, George Wenfu Silverman, Robert Radu, Caius G. Witte, Owen N. Lee, Ki-Bum ...

Published in Biomedical Microdevices

The development of miniaturized cell culture platforms for performing parallel cultures and combinatorial assays is important in cell biology from the single-cell level to the system level. In this paper we developed an integrated microfluidic cell-culture platform, Cell-microChip (Cell-μChip), for parallel analyses of the effects of microenvironme...

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